Route Description
Created in 2004, the Sierra route traverses the southwestern desert climates of West Texas, New Mexico, Arizona, and Utah before heading north up the California, Oregon, and Washington coasts and into British Columbia and the Yukon before finally reaching Alaska. The route stops in large cities, small towns, and national parks along the way, including: Zion National Park, UT; Yosemite National Park, CA; South Lake Tahoe, CA; San Francisco, CA; Portland, OR; Seattle, WA; Vancouver, BC; Prince George, BC; and Whitehorse, YT. The Sierra route was one of the two original routes that were created when Texas 4000 was founded in 2004.
Current 2025 Route:
| Day | Day of week | Date | Sierra Ending Location |
| 0 | Friday | May-16 | Austin, TX |
| 1 | Saturday | May-17 | Lometa, TX |
| 2 | Sunday | May-18 | Brownwood, TX |
| 3 | Monday | May-19 | Abilene, TX |
| 4 | Tuesday | May-20 | Snyder, TX |
| 5 | Wednesday | May-21 | Lubbock, TX |
| 6 | Thursday | May-22 | Clovis, NM |
| 7 | Friday | May-23 | Santa Fe, NM |
| 8 | Saturday | May-24 | Grand Canyon NP |
| 9 | Sunday | May-25 | Page, AZ |
| 10 | Monday | May-26 | Kanab, UT |
| 11 | Tuesday | May-27 | Zion National Park |
| 12 | Wednesday | May-28 | Zion National Park [REST] |
| 13 | Thursday | May-29 | Las Vegas, NV |
| 14 | Friday | May-30 | Bishop, CA |
| 15 | Saturday | May-31 | June Lake, CA (Mammoth) |
| 16 | Sunday | Jun-1 | Lee Vining, CA (Yosemite) |
| 17 | Monday | Jun-2 | Topaz Lake, NV |
| 18 | Tuesday | Jun-3 | South Lake Tahoe, CA |
| 19 | Wednesday | Jun-4 | South Lake Tahoe, CA [REST] |
| 20 | Thursday | Jun-5 | Davis, CA |
| 21 | Friday | Jun-6 | Napa, CA |
| 22 | Saturday | Jun-7 | San Francisco, CA |
| 23 | Sunday | Jun-8 | San Francisco, CA – [REST] |
| 24 | Monday | Jun-9 | Santa Rosa, CA |
| 25 | Tuesday | Jun-10 | Fort Bragg, CA |
| 26 | Wednesday | Jun-11 | Redway, CA |
| 27 | Thursday | Jun-12 | Hydesville, CA |
| 28 | Friday | Jun-13 | Mill Creek Campground |
| 29 | Saturday | Jun-14 | Gold Beach, OR |
| 30 | Sunday | Jun-15 | Coos Bay, OR |
| 31 | Monday | Jun-16 | Florence, OR |
| 32 | Tuesday | Jun-17 | Eugene, OR |
| 33 | Wednesday | Jun-18 | Albany, OR |
| 34 | Thursday | Jun-19 | Portland, OR |
| 35 | Friday | Jun-20 | Portland, OR – [REST] |
| 36 | Saturday | Jun-21 | Longview, WA |
| 37 | Sunday | Jun-22 | Olympia, WA |
| 38 | Monday | Jun-23 | Seattle, WA |
| 39 | Tuesday | Jun-24 | Anacortes, WA |
| 40 | Wednesday | Jun-25 | Vancouver, BC |
| 41 | Thursday | Jun-26 | Vancouver, BC [REST] |
| 42 | Friday | Jun-27 | Whistler, BC |
| 43 | Saturday | Jun-28 | Lillooet, BC |
| 44 | Sunday | Jun-29 | 100 Mile House, BC |
| 45 | Monday | Jun-30 | Williams Lake, BC |
| 46 | Tuesday | Jul-1 | Quesnel, BC |
| 47 | Wednesday | Jul-2 | Prince George, BC |
| 48 | Thursday | Jul-3 | Prince George, BC [REST] |
| 49 | Friday | Jul-4 | Beaumont Provincial Park, BC |
| 50 | Saturday | Jul-5 | Burns Lake, BC |
| 51 | Sunday | Jul-6 | Smithers, BC |
| 52 | Monday | Jul-7 | Hazelton, BC |
| 53 | Tuesday | Jul-8 | Cranberry Junction |
| 54 | Wednesday | Jul-9 | Meziadin Junction, BC |
| 55 | Thursday | Jul-10 | Iskut, BC |
| 56 | Friday | Jul-11 | Dease Lake, BC |
| 57 | Saturday | Jul-12 | Jade City, BC |
| 58 | Sunday | Jul-13 | Watson Lake, YT |
| 59 | Monday | Jul-14 | Johnson’s Crossing, YT |
| 60 | Tuesday | Jul-15 | Whitehorse, YT |
| 61 | Wednesday | Jul-16 | Whitehorse, YT [REST] |
| 62 | Thursday | Jul-17 | Haines Junction, YT |
| 63 | Friday | Jul-18 | Burwash Landing, YT |
| 64 | Saturday | Jul-19 | Beaver Creek, YT |
| 65 | Sunday | Jul-20 | Tok, AK |
| 66 | Monday | Jul-21 | Chistochina, AK |
| 67 | Tuesday | Jul-22 | Glenallen, AK |
| 68 | Wednesday | Jul-23 | Nelchina, AK |
| 69 | Thursday | Jul-24 | Wasilla, AK |
| 70 | Friday | Jul-25 | Anchorage, AK |